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We evaluated the efficacy and safety of gabapentine administered as monotherapy in an 8-day,randomized,double-blind,dose-controlled,parallel- group,multicenter study comparing dosages of 300 and 3,600 mg/d gabapentin in 82 hospitalized patients whose antiepileptic medications had been discontinued for seizure monitoring.These results demonstrate that gabapentin has anticonvulsant activity and is well tolerated when administered as monotherapy in patients with refractory partial seizures. |
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gabapentin
seizure
seizure,focal
seizure,intractable
seizure,intractable,treatment of
seizure,psychomotor-temporal lobe
seizure,treatment of
seizure,treatment of,monotherapy
treatment of neurologic disorder
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